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For Research Use Only (RUO)

This product is not intended for human consumption, therapeutic application, or veterinary purposes. Read our research disclaimer

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Melanotan-1 10mg

For Research Use Only (RUO)

≥99% Purity
EU Stock – 2–6 business day EU shippingFree shipping over €115

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Ordering information

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For qualified laboratory research only (RUO). Not for use in humans or animals.

Bacteriostatic Water
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Free Bacteriostatic Water

Included with every peptide order

Overview: Melanotan-1 (MT-1, Afamelanotide, [Nle⁴, D-Phe⁷]-α-MSH, NDP-α-MSH) is a synthetic linear 13-amino acid analogue of alpha-melanocyte-stimulating hormone (α-MSH). Neuroscience & Endocrinology category: a highly selective agonist of the Melanocortin-1 Receptor (MC1R) with significantly increased metabolic stability compared to native α-MSH.

Research Purpose: Investigation of MC1R-mediated melanin synthesis (eumelanin content, tyrosinase activation), photoprotection studies in cultured melanocytes, cAMP signalling cascade analyses, and structure-activity relationships of linear α-MSH analogues.

Specifications: ≥99% purity (HPLC + LC-MS), batch tracking, lyophilised. Nle⁴ and D-Phe⁷ substitutions for protease resistance. COA included. 100% EU shipping guarantee – free replacement for loss or damage.

Research Purpose

  • Melanocortin Receptor Research: Selective MC1R activation and binding studies in melanocyte models.
  • Photoprotection Studies: Analysis of UV-induced melanin synthesis and eumelanin/phaeomelanin ratios in vitro.
  • Signalling Pathway Analyses: Investigation of the cAMP/PKA signalling cascade and tyrosinase activation.
  • Peptide Chemistry: Comparative SAR studies of linear vs. cyclic α-MSH analogues.
  • Purity ≥99% verified by HPLC
  • Linear 13-amino acid α-MSH analogue
  • Selective MC1R agonist
  • Nle⁴/D-Phe⁷ – high metabolic stability
  • Full batch traceability

Frequently asked questions

What is Melanotan-1?

Melanotan-1 (Afamelanotide, NDP-α-MSH) is a synthetic linear 13-amino acid analogue of α-MSH and a highly selective agonist of the Melanocortin-1 Receptor (MC1R). Due to Nle⁴ and D-Phe⁷ substitutions, it is more protease-resistant than native α-MSH.

What distinguishes Melanotan-1 from Melanotan-2?

MT-1 is a linear peptide with high MC1R selectivity. MT-2 is a cyclic heptapeptide and activates MC1R, MC3R, MC4R, and MC5R more broadly. MT-1 is typically used for targeted MC1R studies.

How should I store Melanotan-1?

Store lyophilised product at 2–8 °C, protected from light and moisture. Reconstituted solutions are typically stored cold and protected from light in research settings; stability testing is the responsibility of the respective laboratory.

Is Melanotan-1 the same as Afamelanotide?

Yes – Melanotan-1 is the common name for [Nle⁴, D-Phe⁷]-α-MSH (NDP-α-MSH). Afamelanotide is the INN name for the same sequence, which has been investigated clinically for EPP. NovaCell supplies this peptide exclusively for RUO.

Is Melanotan-1 intended for use in humans?

No. Melanotan-1 from NovaCell is intended exclusively for research purposes (Research Use Only).

Batch record: every lab report

Every batch is analysed before it is sold. These are all published reports for this product – with report number, date and a PDF you can check.

BatchReport no.DatePurity (HPLC)EndotoxinLabPDF
M1-082604Lyo-1050Oct 2026>99.8%–Liquilabs PDF

View all lab reports

Analyses by external, independent testing laboratories (Liquilabs). Every report has its own analysis number and can be viewed as a PDF or on the lab's verification page.

Supplier: NCBL Sciences OÜ (Estonia), registry code 17455124 · shipped from our EU warehouse in Poland.

All products strictly for research and laboratory use (RUO).

Peptides from the same research category – HPLC + LC-MS tested, with COA.

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For Research Use Only (RUO). Not for human consumption or veterinary use. No medical recommendations. Full Disclaimer

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